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Educational Articles

  • Pilocarpine is used off-label and given by mouth in food to treat neurogenic keratoconjunctivitis sicca, and used topically in the eye to diagnose cranial nerve III problems. Common side effects include irritation of the eye, and more severe side effects include vomiting, diarrhea, increased salivation and urination, and coughing. Do not use in pets that are allergic to it or that have secondary glaucoma.

  • Pimobendan is a medication given by mouth as a tablet or liquid, used to treat congestive heart failure in dogs. Its use in cats is off label. The most common side effects include decreased appetite and diarrhea.

  • Pituitary macroadenomas are large tumors of the pituitary gland that are either functional (secrete hormones) or non-functional (do not secrete hormones). The clinical signs depend on the type of macroadenoma, though become severe over time in either case. Diagnosis requires specialized CT or MRI imaging. This handout explains the effects of macroadenomas in cats and the treatment options available.

  • Clinical signs of pituitary tumors depend on whether the tumor is functional or non-functional. Functional tumors can cause Cushing's disease in dogs and can cause acromegaly and insulin-resistant diabetes in cats. Non-functional pituitary tumors can enlarge to cause neurological signs. Diagnosis is based on the history, bloodwork, urinalysis, and sometimes a CT scan or MRI. Medical therapy is often the treatment of choice for functional tumors. Radiation therapy is another option and is usually the primary treatment for non-functional tumors.

  • Bouquets and plants make wonderful gifts and decorations for our homes. However, many plant species can be hazardous to your cat's health. Be aware of the plants and flowers you are bringing into your home to prevent accidental poisonings. This handout outlines several common toxic plants.

  • Plaque forms on teeth shortly after eating and within 24 hours begins to harden, eventually turning into tartar. Tartar serves as a place for bacteria to grow, leading to gingivitis. As gingivitis worsens, periodontal disease develops, which includes inflammation, pain, and tooth loss. Prevention of plaque and tartar build-up is key. Use VOHC-accepted food and/or water additives, wipe or brush your cat's teeth daily, and have your veterinarian perform regular dental cleanings.

  • Plasma cell tumors develop as a result of dysregulated production of plasma cells and are relatively uncommon in dogs and cats. Some plasma cell tumors are benign and the most common locations for these tumors are the head, feet, lips, mouth, and ears. The treatment of choice for benign plasma cell tumors is surgical removal, with little to no recurrence if completely excised. Conversely, multiple myeloma is a very malignant cancer that is usually treated with chemotherapy.

  • Platelet-rich plasma or PRP is a form of regenerative medicine where the platelet and protein components of blood are retrieved from a patient and then injected back into the patient at the site of inflammation. PRP contains growth factors that appear to promote tissue regeneration and reduce inflammation. The procedure is not yet widely available and should only be performed by a veterinarian with specialized equipment and special training in this area.

  • Some cats do not seem to know their strength and do not recognize that they are causing pain to their play partners. Accidental bites and scratches can be painful and cause infection, so it is important to find ways to play safely. With training, you may be able to use a verbal cue to redirect your cat if he becomes overly aroused during play.

  • Pleural effusion refers to the abnormal accumulation of fluid within the chest cavity. The fluid is not found within the lungs, but instead within the pleural sac, essentially meaning the lungs are floating in a chest that is full of fluid. Several conditions can cause pleural effusion, including chylothorax, heart failure, and tumors in the lungs or chest wall. Immediate treatment often requires oxygen support and the removal of the excess fluid by thoracocentesis, which can also then be tested to diagnose the cause of the pleural effusion. Treatment and prognosis vary depending on the underlying cause of the pleural effusion.